Senior Scientist I/II, Oncology

Job Description Summary #LI-Onsite Location: Cambridge, MA This role is based in Cambridge, MA, and does not have the ability to be located remotely. The xDC Biotherapeutics group within Oncology Drug Discovery at Novartis Biomedical Research is seeking a highly motivated and collaborative Senior Scientist I/II to advance drug-conjugate discovery programs for the treatment of cancer patients. In this lab-based role, the successful candidate will apply cell and molecular biology techniques to deliver impactful data for target validation and drug optimization efforts. This role requires a strong understanding of and experience with in vitro cell-based assays for drug discovery. This individual will interact collaboratively with colleagues across Biomedical Research and will be a member of multidisciplinary project teams. This is a great opportunity to join a group dedicated to the discovery of biotherapeutics and to support advancement of drug discovery projects into the Novartis portfolio. Job Description This listing represents multiple openings for the same role. Your Key Responsibilities: Generates hypotheses to test, troubleshoots issues and designs and executes the next set of experiments with some input from senior lab members/manager. Works independently and as a part of a team to design, execute, and analyze in vitro experiments to profile small molecules and biologics and elucidate mechanisms of action Executes cell and molecular biology assays (e.g. cell titer glo, flow cytometry, JESS, western blot, MSD) Cultures cells using sterile technique including genetic engineering and validation of cell lines Uses laboratory automation equipment (liquid handlers, plate readers, dispensers) to perform screens Maintains an organized and detailed record of all experiments Works collaboratively across teams and trains other members of team in areas of technical expertise as needed. Clearly communicates findings and presents research to multidisciplinary project teams Supports lab operations including management of materials, maintenance of instruments, and general lab duties Role Requirements: Essential Requirements: BS/MS Degree in biology or related field Minimum 5+ years of industry experience preferred Extensive experience with cellular assay development & execution, experience with high throughput screening workflows strongly preferred Demonstrated ability to analyze, interpret and present data in a clear manner and use data to generate new hypotheses Highly self-motivated, collaborative team player with exceptional organizational skills and curiosity to expand and diversify skillsets Level will commensurate with experience Desired Requirements : Oncology experience highly preferred Understanding of drug discovery optimization processes Experience with discovery of antibody-drug-conjugates Novartis Compensation and Benefit Summary: Role Leveling (Dual Posting) This is a dual posting. The final level and title will be determined by the hiring team based on skills, experience, and capabilities: The expected salary range at commencement of employment is: Sr Scientist I: $93,800 - $174,200 Sr Scientist II: $98,700 - $183,400 The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. EEO Statement: The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. Accessibility and reasonable accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message. Salary Range $93,800.00 - $174,200.00 Skills Desired Analytical Thinking, Analytical Thinking, Chemical Biology, Chemistry, Clinical Research, Clinical Trials, Collaboration, Communication, Curious Mindset, Data Analysis, Data Management, Design of Experiments (DOE), Detail-Oriented, Diversity and Inclusion (D&I), Drug Discovery Process, Ethics, Gene Therapy, Immunology, Laboratory Research, Leading Project Teams, Life Science, Machine Learning (ML), Mammalian Cell Culture, Medical Research, Molecular Biology {+ 10 more}