Scientist – Neuroimmunology Research

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche! The Opportunity As a Scientist in our Neuroscience and Ophthalmology Discovery team, based at our Roche Innovation Center in Philadelphia, PA (RICP) , you will explore how neuroimmunological mechanisms drive neurodegenerative diseases across the central nervous system, peripheral nervous system, and ocular targets. In this lab-based role, you will conceive and execute preclinical studies that advance promising candidates from early target validation through regulatory submission, collaborating with diverse scientific minds to deliver transformative therapies for patients. Drive Preclinical Discovery: Conceive, initiate, and execute laboratory research to advance neuroimmunology candidates from target validation to investigational new drug (IND) readiness. Lead Laboratory Innovation: Investigate scientific concepts and design cutting-edge in vitro and in vivo disease models to validate novel therapeutic targets and mechanisms. Serve as a Scientific Partner: Provide subject matter expertise in neuroimmunology across cross-functional discovery teams, advising on ocular and neurodegenerative research programs. Champion Collaboration: Build and manage dynamic research partnerships with global internal teams, academic collaborators, and contract research organizations (CROs). Share Knowledge & Insights: Analyze complex experimental datasets, author study reports and regulatory documentation, and present discoveries at international scientific conferences. Shape Intellectual Property: Contribute to patent applications and scientific publications that advance the field of neurodegenerative disease research. Who You Are You bring curiosity, scientific rigor, and a collaborative mindset to tackling complex biological questions. You thrive at the laboratory bench, communicate ideas with clarity and empathy, and are eager to contribute to an open environment where diverse perspectives spark innovation. You hold a PhD in Immunology, Neuroscience, or a closely related biological discipline, paired with at least 2 years of relevant postdoctoral or industry research experience. You possess hands-on expertise in advanced immunology laboratory techniques, such as flow cytometry, cell sorting, immunoassays (ELISA, MSD, Western Blotting), and molecular methods (qPCR/ddPCR). You demonstrate deep knowledge of neuroimmune biology and experience developing functional cell-based assays for target validation or protein modulation. You bring proven experience building and characterizing relevant disease models, including iPSC-derived CNS models is strongly preferred. You have a track record of rigorous data analysis and scientific problem-solving. You communicate and collaborate effectively within multidisciplinary teams, adapting flexibly to project priorities. Relocation benefits are not available for this job posting. The expected salary range for this position based on the primary location of Philadelphia, PA is $108,100 - $200,700. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the links provided below. Benefits ( Summary | Detail ) Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants .