Site Management and Monitoring Hub Head (oncology)

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company dedicated to discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading biopharmaceutical companies—we are also a Great Place to Work . At AstraZeneca, we put patients first and are driven to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking boldly and collaborating to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate and curious about what science can achieve , you could be the person we are looking for. Role Description The Site Management and Monitoring (SMM) organisation, with colleagues across the globe, is responsible for global site management delivery across the Oncology portfolio. Reporting to the Global Head, SMM Oncology , the Oncology SMM Hub Leader will provide expert input to global Therapy Area (TA) partners, translating the Oncology clinical development strategy into a regional clinical site and market operational plan. You will drive operational delivery excellence and oversee the timely, high-quality, ethical and compliant delivery of interventional trials across the assigned region, which includes the USA and Canada . You will also be accountable for the consistent maintenance and development of SMM frameworks that support delivery of AstraZeneca’s Oncology and Haematology portfolio. Typical Accountabilities Strategy and operational excellence : Understand the critical success factors for the global Oncology strategy and ensure operational excellence across all markets in the region. Use external competitor intelligence and industry trends to continuously improve performance, benchmark against best-in-class metrics and help ensure AstraZeneca delivers in the top quartile of the industry. Regional alignment : Align regional objectives with global Site Management and Monitoring priorities, translating global strategy into effective market-level delivery. Study leadership and monitoring practices : Identify and implement regional study leadership and monitoring practices aligned with Therapy Area needs. Optimise the use of digital strategies and industry trends, while ensuring appropriate resources are in place for all SMM roles required to deliver the strategy at market level. Cross-functional collaboration : Drive collaboration across market-level functions, including Medical Affairs, Regulatory, Payor and institutional partners. Outsourcing and people agenda : Lead the implementation of outsourcing strategies to establish efficient and flexible sourcing models. Build a strong people agenda, ensuring the function and its people are appropriately trained, equipped and ready to deliver. Innovation and capability development : Lead and promote excellence across markets, Therapy Areas and geographies within the region. Identify external trends that enable the effective deployment of skills, assets and technologies to meet partner requirements. Maintain and develop frameworks that support exciting, innovative and effective ways of working with partners. Processes and systems : Ensure excellence in the development and implementation of processes and systems for clinical trial conduct. Budget and resource management : Build, lead, forecast and update budgets; forecast resource requirements; and, where critical to the business, implement systems and processes to staff countries efficiently. Coordinate financial reporting and ensure adherence to relevant procedures. Performance metrics : Lead all aspects of the regional SMM contribution to the global development site operations metrics dashboard, ensuring delivery against clearly defined quality and speed metrics. Compliance : Ensure compliance with ICH/GCP regulations, including applicable CFR requirements. Continuous improvement : Contribute to the continuous improvement of SMM operations and foster the sharing of best practices across regions, countries and departments. Portfolio delivery : Identify and lead opportunities for portfolio delivery and synergies across countries within the region. Leadership and development : Hire, manage, develop and recognise the performance of direct reports. Education, Qualifications, Skills and Experience Essential Bachelor’s degree or equivalent qualification in a relevant scientific discipline. At least 10 years of relevant experience with focus on Development and Patient Safety. Relevant pharmaceutical experience (big pharma) Leadership experience in a complex environment. Ability to communicate effectively with stakeholders across AstraZeneca. Mastery of the Clinical Development area, with multidisciplinary experience across functions or within a functional area. Desired PhD in a scientific discipline. An expert reputation within the business and industry, with extensive knowledge of the latest technical and regulatory expectations. Ability to engage, influence and collaborate across boundaries, with a strong problem-solving and delivery focus. Ability to assimilate sophisticated information, identify key issues and communicate clear messages. Functional management experience, including resource management, budget planning and functional planning. For the full time role, the annual base salary in for this position in the US, ranges from $304,856 - $457,285 USD. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) or to receive a retirement contribution (hourly roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Date Posted 24-Oct-2026 Closing Date 09-Nov-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.