ApplySarthi

Lead Software Engineer (Back-End Engineer)

Cadence

Tailor my CV for this job, freeView job and applyYour CV rewritten for this role, from your real experience. Sign in with Google, nothing to install.

Got this interview? Our apps help you get the job.

Skills named in this job

Read from the description itself, not inferred.

This role on the market

11,833 open software roles across 806 companies are on ApplySarthi right now, most of them in Bengaluru (805), Hyderabad (303), Pune (189).

What software roles keep asking for: Python (30%), Java (29%), AWS (28%), System design (25%), C++ (21%), CI/CD (20%), Observability (20%), Kubernetes (19%) — counted across their open postings here.

Software Engineer jobs in Bengaluru · Software Engineer jobs in India · Remote Software Engineer jobs · AWS jobs · CI/CD jobs · Customer success jobs · Django jobs

Cadence has 590 open roles listed here.

Counted across 14 company job boards, updated as roles open and close.

Preparing for this interview

Interviews for software roles keep coming back to Python, Java, AWS, System design. Practise those questions before you sit with Cadence.

Questions you are likely to be asked

  1. Why do you want to join Cadence?
  2. What is your experience with AWS? Tell me one thing you learned the hard way.
  3. What do you do when a production issue happens on your code?
  4. Walk me through a system you built. How was it designed, and what would you change now?
  5. Tell me about a hard bug you tracked down. How did you find the cause?

Prep Sarthi gives you a free mock interview: an AI interviewer asks you questions like these out loud, from your own CV and this job, and shows your score and your weakest answer.

Practise the Lead Software Engineer (Back-End Engineer) at Cadence interview free →

At Cadence, we hire and develop leaders and innovators who want to make an impact on the world of technology. Job Summary: Scientists around the world use Orion for early-stage drug discovery and design in the pursuit of improving human health. Orion combines the power of advanced HPC, computational methods, and in-browser 3D visualization & modeling to solve problems in drug discovery & design. Our innovative solutions enable customers to routinely model billions of compounds in-silico. Orion enables our customers to interactively explore chemical space, evaluate designs and gain scientific understanding. As a Back-End Engineer, you’ll work with designers, scientists, and software engineers to enhance & extend Orion's capabilities -- architecting and optimizing the high-performance compute and storage systems that drive groundbreaking scientific discoveries. You'll be part of a team building cutting edge features, as well as helping to modernize existing software. Qualifications & Experience: Bachelor’s degree in computer science/engineering, biology/chemistry or similar 5+ years of experience designing, developing, troubleshooting and debugging complex distributed systems as part of a team Expert in Python, pytest, packaging, and Django Expert in GoLang, testing, packaging, and client/server, and familiarity with writing servers/clients Experience with PostgreSQL, SQLite, and relational database optimization and structural design Experience in Life Sciences, HPC, AWS, Docker, and containerized systems Experience with unit & end-to-end testing, CI/CD, source control, code review, comfortable using command line interfaces Strong background of computer science fundamentals (data structures, algorithms) Passionate to learn and explore new technologies and demonstrates good analysis and problem-solving skills Interpersonal skills required: Ability to establish a close working relationship with peers in development, science, design and customer success, often across time zones Take initiative to solve unexpected challenges during development Willing to expand their knowledge and skills in both technical and scientific areas Push to raise the bar while always operating with integrity OpenEye, Cadence Molecular Sciences is passionate about science and about taking care of team members, with leaders supporting your development and recognizing your contributions by providing an unmatched total compensation package in a collaborative, caring, energetic and fun work environment. We’re doing work that matters. Help us solve what others can’t.

Match this job to your CV

ApplySarthi scores your CV against this role, shows the skills you are missing, and writes a tailored version for the application.

Check my match →

Similar open roles

Need answers during your interview? Try Live Sarthi.

Live Sarthi, an Interview Sarthi app, shows answer suggestions during the call.

Try Live Sarthi free →

A Windows app, from the same team as ApplySarthi.

Listed on workday · posted 2026-09-06. ApplySarthi collects openings and links to application pages; the role is advertised by Cadence, not by us.