Early Development Leader (Oncology R & D)

For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge. The location of this role will therefore subsequently change to Cambridge in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029. Business Introduction At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together. Find out more: Our approach to R&D Job Purpose As the Early Development Leader (EDL), you will lead the early development of oncology medicines from candidate selection through proof of concept. As the single point of accountability for your asset, you will set a clear strategy, make evidence-based go/no-go decisions, and partner with teams across research, clinical development, medical, regulatory, and commercial functions. We value scientific curiosity, decisive leadership, strong collaboration, and an unwavering focus on patient impact. This role offers significant growth potential and visible influence across the pipeline. Key Responsibilities This role will provide you with the opportunity to lead high-impact activities including: Own the early development strategy and serve as the single point of accountability for one or more oncology assets, from candidate selection through proof of concept. Define and drive translational and clinical plans — including experimental medicine studies and biomarker strategies — that support robust go/no-go decisions. Identify key inflection points and make clear, evidence-based decisions to advance or stop programs. Lead cross-functional teams, building alignment across clinical, medical, regulatory, manufacturing, and commercial partners. Engage with external scientific, clinical, and regulatory communities to generate insights that sharpen development plans. Proactively identify regulatory and operational risks, putting mitigation plans in place to keep programs on track. Team and Environment You will join a collaborative, matrixed R&D environment that bridges discovery science and clinical development. Working alongside multidisciplinary colleagues and external partners, you will design and deliver robust early development programs. We encourage open scientific discussion and practical problem-solving that accelerates development while upholding the highest scientific standards. Basic Qualifications We're looking for professionals who bring: An advanced scientific or medical degree (MD, PhD, PharmD, or equivalent), or a relevant bachelor's degree paired with substantial oncology development experience. Proven experience in early-stage oncology drug development, including translational medicine and experimental medicine design. A demonstrated ability to translate preclinical data into actionable clinical development plans. Experience leading cross-functional teams in a matrix environment and driving decisions across diverse stakeholders. A track record of evidence-based go/no-go decision-making and defining clear development inflection points. Strong communication skills, with the ability to present complex scientific plans clearly to both internal colleagues and external stakeholders. Preferred Qualifications Three or more years leading oncology development programs, including experience preparing regulatory filings to initiate clinical testing. Experience with biomarker strategy development and clinical pharmacology considerations for first-in-human studies. A track record engaging external advisors, key opinion leaders, and patient communities. Experience in business development, due diligence, or partnership integration activities. Demonstrated skill in developing leaders and building high-performing teams Ability to apply late-stage development and commercial launch insight to early-stage strategy PLEASE NOTE: This career opportunity offers hybrid working and requires an on-site office presence (minimum of two days a week) at one of GSK’s UK (Stevenage or London HQ); US (Collegeville, PA or Waltham, MA) sites. Apply now If you are ready to shape early development strategy and make a measurable difference for patients, we want to hear from you. Please submit your application and include a brief note about what motivates you to work in oncology early development. Skills Business Strategies, Commercial Acumen, Digital Fluency, Drug Development, Drug Regulatory Affairs, Evidence Based Decision Making, Executive Presence, Hematology and Oncology, Innovative Leadership, Matrix Leadership, Prioritization, Project Development, Scientific Data Analysis, Scientific Presentations, Team Development • If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $202,500 to $337,500. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process. Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments@gsk.com GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. 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