Staff / Principal Research Engineer, AI Safety Mitigations
Lilasciences
Tailor my CV for this job, freeView job and applyYour CV rewritten for this role, from your real experience. Sign in with Google, nothing to install.
Got this interview? Our apps help you get the job.
Skills named in this job
Read from the description itself, not inferred.
This role on the market
4 open mitigations roles across 3 companies are on ApplySarthi right now.
- Workstream Lead, Agentic AI Risk Modelling and MitigationsAisi
- Researcher, Agent Safety, Oversight and System MitigationsOpenai
What mitigations roles keep asking for: Machine learning (50%), Python (25%), Talent acquisition (25%) — counted across their open postings here.
Lilasciences has 6 open roles listed here.
- Staff Software Engineer, AI Safety
- Staff / Principal Security Engineer, AI Safety and Security
- Senior Specialist / Manager, AI Safety Data and Evaluation Program
- Senior / Principal Chemist, AI Safety
- Director/Senior Director, Molecular Discovery
Counted across 14 company job boards, updated as roles open and close.
Preparing for this interview
Interviews for mitigations roles keep coming back to Machine learning, Python, Talent acquisition. Practise those questions before you sit with Lilasciences.
Questions you are likely to be asked
- Why do you want to join Lilasciences?
- What is your experience with Talent acquisition? Tell me one thing you learned the hard way.
- Tell me about a time the data was messy or wrong. What did you do?
- How would you explain your model's result to someone who is not technical?
- What would you check first if a model's accuracy dropped after going live?
Prep Sarthi gives you a free mock interview: an AI interviewer asks you questions like these out loud, from your own CV and this job, and shows your score and your weakest answer.
Practise the Staff / Principal Research Engineer, AI Safety Mitigations at Lilasciences interview free →Your Impact at LILA
We're building a talent-dense, high-agency AI safety team at Lila that will engage all core teams within the organization (science, model training, lab integration, etc.), to identify and mitigate risks from scientific superintelligence while retaining the core scientific discovery capabilities of the stack. The initial focus of this team will be to build and implement a bespoke safety strategy for Lila, tailored to its specific goals and deployment strategies. This will involve technical safety strategy development, broader ecosystem engagement, safety-focused evaluations, safety systems to mitigate risks, and a research agenda that explores longer-term needs such as oversight of superintelligent scientific systems.
At Lila Sciences, you will develop and test safeguards that reduce societal risks from increasingly capable closed loop scientific AI. This is a high-priority individual contributor role for an engineer who has built safety interventions within the development and deployment of frontier models and wants to apply that experience to scientific models, agents, tools and laboratory-connected workflows.
You will work with domain scientists, risk researchers, evaluators and engineering teams to turn risk findings and policy requirements into effective interventions. The work spans research and implementation: developing approaches, testing their limits and helping integrate reliable safeguards into the systems where they are needed. We are open to different levels of seniority and depth across mitigation approaches.
What You'll Be Building
- Translate scientific risk assessments, dual-use policy boundaries and evaluation findings into concrete mitigation designs and testable requirements.
- Develop and implement safeguards suited to the problem, potentially spanning model training, classifiers, monitoring, access controls and runtime interventions.
- Build experiments that measure risk reduction, robustness and effects on legitimate scientific use, alongside practical performance constraints.
- Use adversarial findings and observed failures to improve safeguards, working closely with automated-safety and scientific evaluation researchers.
- Work directly with model-training, post-training, inference and platform teams to integrate mitigations into model development, release evaluation and large-scale serving systems, with appropriate instrumentation and reproducible testing.
- Investigate regressions, distribution shifts and emerging misuse patterns, and use the evidence to guide further development.
What You'll Need to Succeed
- Hands-on experience developing and validating safety interventions for frontier models within training, post-training or large-scale inference systems, with contributions to model development or release cycles.
- Depth in at least one relevant area, such as safety post-training, model-level classifiers, safeguards integrated into inference, or abuse monitoring and enforcement across a model-serving platform.
- Experience working directly with model-development or safeguards teams, using access appropriate to the intervention—such as training pipelines, model internals, inference infrastructure or systematic evaluation access—to investigate failures and implement improvements.
- Strong research-engineering skills and the ability to move from an ambiguous problem to working, maintainable implementations.
- Sound experimental judgment, including an ability to assess robustness, interpret imperfect metrics and reason about competing objectives.
- The ability to collaborate across research and engineering teams, explain technical trade-offs and take ownership of complex individual contributions.
Bonus Points For
- Experience with scientific models, scientific software or laboratory-connected systems.
- Safety work involving tool-using agents, multi-step workflows or high-consequence misuse.
- Experience connecting expert-generated evidence and policy requirements to training data, evaluation criteria or operational controls.
Compensation
We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.
U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.
International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.
About LILA
Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
We’re All In
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
A Note to Agencies
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.
Match this job to your CV
ApplySarthi scores your CV against this role, shows the skills you are missing, and writes a tailored version for the application.
Check my match →Similar open roles
- Director/Senior Director, Molecular DiscoveryLilasciences
- Senior / Principal Chemist, AI SafetyLilasciences
- Staff Software Engineer, AI SafetyLilasciences
- Staff / Principal Security Engineer, AI Safety and SecurityLilasciences
- Senior Specialist / Manager, AI Safety Data and Evaluation ProgramLilasciences
Need answers during your interview? Try Live Sarthi.
Live Sarthi, an Interview Sarthi app, shows answer suggestions during the call.
- Hidden from supported screen sharingThe overlay stays out of supported Windows screen captures.
- Answers start in about 1.5 secondsResponse time varies with your connection and model.
- From your own CVYour projects and your experience, not a generic script.
- 30 minutes freeThen ₹99 for a 2-day pass with unlimited calls — you pay for the days you are interviewing, not a subscription.
A Windows app, from the same team as ApplySarthi.
Listed on arbeitnow · posted 2026-10-17. ApplySarthi collects openings and links to application pages; the role is advertised by Lilasciences, not by us.